Spravato (Esketamine) for Treatment-Resistant Depression
Spravato is an FDA-approved nasal spray medication for adults with treatment-resistant depression (TRD)—a form of depression that hasn’t improved with traditional antidepressants.
How Spravato Works
Unlike typical antidepressants, Spravato:
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Targets the NMDA receptor, part of the brain’s glutamate system
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Promotes neuroplasticity and more flexible brain connections
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Works faster than standard antidepressants—often within hours or days
Benefits of Spravato Treatment
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✅ Rapid relief from depressive symptoms
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✅ Reduced suicidal thoughts in clinical studies
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✅ Alternative for patients who haven’t responded to other medications
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✅ Used with an oral antidepressant for enhanced effectiveness
Administration & Safety
Spravato is administered in-office under medical supervision due to possible side effects, including:
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Dissociation or disconnection
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Dizziness or sedation
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Nausea
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Not everyone is a candidate for Spravato. A thorough evaluation is required.
Is Spravato Right for You?
If you’ve tried multiple antidepressants without relief, Spravato may be a valuable next step. Talk to your provider about whether this treatment aligns with your needs and medical history.
Contact us today to schedule a consultation and find out if Spravato is the right option for your mental health journey.
Insurance Coverage
Thanks to our partnership with Fairfax TMS, PLLC, we now accept insurance for:
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Spravato treatment
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TMS (Transcranial Magnetic Stimulation) sessions and administration